Haemagglutination
The HA assay is a state-of-the-art method for detection and quantitation of specific viruses. Haemagglutination-is the ability of some viruses to aggregate various species of red blood cells (RBCs). Haemagglutination is the result of interaction of specific virus glycoproteins with surface receptors present on the plasma membrane of RBCs. Not all viruses are capable of causing this reaction and those that do may only react with RBCs of particular species and may do so only under stringent conditions of pH and ionic strength. This is the one of the most common indirect methods of determining virus titer. This assay do not a measure of infectivity.
Downloads complete note....
No comments:
Post a Comment